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MRI in Epilepsy

MRI in Epilepsy PDF Author: Horst Urbach
Publisher: Springer Science & Business Media
ISBN: 3642251382
Category : Medical
Languages : en
Pages : 270

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Book Description
MRI can play an important role in identifying and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy patients and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

MRI in Epilepsy

MRI in Epilepsy PDF Author: Horst Urbach
Publisher: Springer Science & Business Media
ISBN: 3642251382
Category : Medical
Languages : en
Pages : 270

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Book Description
MRI can play an important role in identifying and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy patients and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

Magnetic Resonance Scanning and Epilepsy

Magnetic Resonance Scanning and Epilepsy PDF Author: Simon D. Shorvon
Publisher: Springer Science & Business Media
ISBN: 1461525462
Category : Medical
Languages : en
Pages : 323

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Book Description
It was only in 1980 that the first recognisable magnetic resonance images of the human brain were published, by Moore and Holland from Nottingham University in England. There then followed a number of clinical trials of brain imaging, the most notable from the Hammersmith Hospital in London using a system designed by EMI, the original manufacturers of the first CT machines. A true revolution in medicine has ensued; in only a few years there are thousands of scanning units, and magnetic resonance imaging (MRI) has assumed a central importance in medical investigation. It is an extraordinary fact that within a few years of development, the esoteric physics of nuclear spin, angular momentum, and magnetic vector precession were harnessed to provide exquisite images of living anatomy; modem science has no greater tribute. That indisputable king of neurology and the oldest of recorded conditions, epilepsy, has not been untouched by the new technology; indeed, it is our view that the introduction of MRI of electroencephalography (EEG) in the late has been as important to epilepsy as was that 1930s. Now, for the first time, the structural and aetiological basis of the condition is susceptible to thorough investigation, and MRI can provide structural detail to parallel the functional detail of EEG. MRI has the same potential as had EEG over 50 years ago, to provide a new level of understanding of the basic mechanisms, the clinical features and the treatment of epilepsy.

MRI-Negative Epilepsy

MRI-Negative Epilepsy PDF Author: Elson L. So
Publisher: Cambridge University Press
ISBN: 110703423X
Category : Medical
Languages : en
Pages : 255

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Book Description
This book critically appraises the role and value of specific diagnostic and treatment techniques for drug-resistant, MRI-negative epilepsy. The authors present the evidence and share their expertise on the diagnostic options and surgical approaches that make epilepsy surgery possible and worthwhile in this complex and challenging condition.

Magnetic Resonance in Epilepsy

Magnetic Resonance in Epilepsy PDF Author: Ruben Kuzniecky
Publisher: Academic Press
ISBN: 9780080535715
Category : Medical
Languages : en
Pages : 464

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Book Description
Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders. *Provides a crucial update of recent advances in imaging techniques *Timely publication as subject of neuroimaging is a very "hot" area in both clinical epilepsy and basic neuroscience research *Editors are well-respected in this field

Imaging of Epilepsy

Imaging of Epilepsy PDF Author: John M. Stern
Publisher: Springer Nature
ISBN: 3030866726
Category : Brain
Languages : en
Pages :

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Book Description
This clinically-oriented collection of brain imaging results provides a unique and helpful approach to the epilepsy evaluation. The atlas is divided into sections according to general clinical categories with each category including a collection of clinical examples that span the category. Each example includes images across the relevant imaging modalities that relate to one patient, whose history accompanies the images. This case-based organization with clinical history and multiple images offers a complete visual understanding of the imaging findings and the corresponding relationship of each finding to the clinical presentation, treatment, and outcome. Images for the book are from the UCLA Seizure Disorder Center, which is a referral center that serves a large outpatient epilepsy patient population and performs approximately 500 inpatient epilepsy evaluations annually. Comprehensive and richly illustrated, this book will serve as a convenient resource in neurologic and radiologic practice, and useful for board exam review.

Imaging Biomarkers in Epilepsy

Imaging Biomarkers in Epilepsy PDF Author: Andrea Bernasconi
Publisher: Cambridge University Press
ISBN: 1108577415
Category : Medical
Languages : en
Pages :

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Book Description
Epilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.

Feature Analysis of Functional MRI Data for Mapping Epileptic Networks

Feature Analysis of Functional MRI Data for Mapping Epileptic Networks PDF Author: Lauren S. Burrell
Publisher:
ISBN:
Category : Brain
Languages : en
Pages :

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Book Description
This research focused on the development of a methodology for analyzing functional magnetic resonance imaging (fMRI) data collected from patients with epilepsy in order to map epileptic networks. Epilepsy, a chronic neurological disorder characterized by recurrent, unprovoked seizures, affects up to 1% of the world's population. Antiepileptic drug therapies either do not successfully control seizures or have unacceptable side effects in over 30% of patients. Approximately one-third of patients whose seizures cannot be controlled by medication are candidates for surgical removal of the affected area of the brain, potentially rendering them seizure free. Accurate localization of the epileptogenic focus, i.e., the area of seizure onset, is critical for the best surgical outcome. The main objective of the research was to develop a set of fMRI data features that could be used to distinguish between normal brain tissue and the epileptic focus. To determine the best combination of features from various domains for mapping the focus, genetic programming and several feature selection methods were employed. These composite features and feature sets were subsequently used to train a classifier capable of discriminating between the two classes of voxels. The classifier was then applied to a separate testing set in order to generate maps showing brain voxels labeled as either normal or epileptogenic based on the best feature or set of features. It should be noted that although this work focuses on the application of fMRI analysis to epilepsy data, similar techniques could be used when studying brain activations due to other sources. In addition to investigating in vivo data collected from temporal lobe epilepsy patients with uncertain epileptic foci, phantom (simulated) data were created and processed to provide quantitative measures of the efficacy of the techniques.

Brain Imaging in Epilepsy

Brain Imaging in Epilepsy PDF Author: David D. Maudgil
Publisher: Remedica
ISBN: 1901346242
Category : Health & Fitness
Languages : en
Pages : 80

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Book Description
Recent advances in functional neuroimaging have greatly enhanced our understanding of brain functionality through the ability to visualize brain processes at work. Brain Imaging in Epilepsy provides an overview of the techniques that have been developed, including positron emission tomography (PET), single photon emission computed tomography (SPECT), functional magnetic resonance imaging (fMRI), diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS). Relevant features of the basic neuroscience of epilepsy are reviewed, and the application of these techniques in diagnosing, treating and developing new treatments for epilepsy is discussed. This book will prove fascinating to a large audience from practicing neurologists and radiologists, to junior doctors and students of medicine, neuroscience and medical physics.

Pediatric Neurology Part I

Pediatric Neurology Part I PDF Author: Friedrich G. Woermann
Publisher: Elsevier Inc. Chapters
ISBN: 0128077824
Category : Medical
Languages : en
Pages : 892

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Book Description
Malformations of cortical development, especially focal cortical dysplasia in infants and children, and hippocampal sclerosis in adolescents with epilepsy are frequent lesions, but they are overlooked on standard MRI. In infants, errors in the interpretation of MRI in epilepsy can be attributed to MRI signal changes due to ongoing myelination. Poor technique, perceptual misses, incomplete knowledge and poor judgment are, however, other likely sources of errors when reading MRIs. This review covers MRI search strategies, i.e., how to conduct MRI examinations in epilepsy and what to expect in the structural MRI of an infant or child with focal epilepsy. Exploiting increased sensitivity, false positive results can be avoided in the light of a clinical hypothesis, possibly isolating a localized brain area by seizure semiology, EEG, and sometimes PET prior to MR reading.

Magnetic Resonance in Epilepsy

Magnetic Resonance in Epilepsy PDF Author: Ruben I. Kuzniecky
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 345

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Book Description